• Get the exact sequence you need. The GeneMaker^® technology with error correction and sequence verification will synthesize the sequence exactly as it is ordered.
• Fast. Many sequences (length- and complexity-dependant) are delivered within 2 to 4 weeks.
• Guaranteed quality. We guarantee the sequence delivered will exactly match the sequence ordered.
• Save money. Synthesis costs less than in-house cloning for many genes.
• Save time and labor. We are the experts at synthesis; you are the experts at discovery using the sequences we send you.
• Secure and confidential. Order and communicate via a password protected, dedicated website.
• Defined pricing. Know your project costs before starting on a project using our Quote Tool.
• No claim to your inventions. You own full right and title to the products delivered and you retain your intellectual property rights.
• Optional sequence design. Blue Heron Bio's Codon or Expression Optimization converts your amino acid sequence into a DNA sequence to suit your downstream expression needs.
• Excellent service. We focus on service for every detail, from setting up your account to delivering your order quickly and accurately.
• Trust experience. Blue Heron Bio has extensive experience, having synthesized and shipped thousands of genes with perfect accuracy.

At current prices, gene synthesis from Blue Heron Biotechnology costs less than PCR for most genes. To save time and money, we recommend that you outsource all gene synthesis to concentrate on your core discovery efforts. Here is why:

• Blue Heron Bio's gene synthesis services are typically less expensive than most PCR cloning attempts
  Use GeneMaker® to provide certainty of delivery and perfect quality.
• Blue Heron Bio can synthesize the majority of sequences but PCR is uncertain
  PCR's uncertain success rate jeopardizes your budget and your timeline. While success rates for genes less than 200bp are greater than 90%, the rate drops to 60% for genes greater than 2250bp, according to data published by BD Biosciences. Because Blue Heron Bio's GeneMaker® platform does not use PCR, it has no sequence biases.
• Using Blue Heron Bio for your synthesis project is a more economical choice for long and complex sequences
  The success rate with PCR and other cloning methods decreases for longer genes, and the time and effort required to clone these genes is less predictable. With GeneMaker®, delivery time and price is predictable, and success is assured. When time and success are important, GeneMaker® offers the most economical method to clone the long genes you need for you research.

The full cost of PCR cloning includes:

• Reagents
• Labor and facility
• Sequencing
• Error correction

Figure 2. Reagents comprise less than one-third of the cost of PCR cloning